What are the manifestations of aniline poisoning? Acute aniline exposure can cause confusion, ringing in the ears, weakness, disorientation, dizziness, impaired gait, lethargy drowsiness, convulsions, loss of consciousness, and coma. These effects are usually transitory
What are the manifestations of aniline poisoning?
Acute aniline exposure can cause confusion, ringing in the ears, weakness, disorientation, dizziness, impaired gait, lethargy drowsiness, convulsions, loss of consciousness, and coma. These effects are usually transitory and probably secondary to lack of oxygen.
Can aniline react with hemoglobin?
Aniline does not readily oxidize hemoglobin in vitro; it must be metabolized to an active form to induce methemoglobinemia (Smith 1996).
What should you do if your skin gets in contact with aniline?
Wash contaminated skin with large amounts of soap and water. Seek medical attention immediately. Begin artificial respiration if breathing has stopped and CPR if necessary.
What are the chemical hazards of aniline?
Flammable. Dangerous for the environment, very toxic for aquatic organisms life with long lasting effects. High heating-up or fire cause decomposition of aniline and formation of highly toxic vapours containing oxides of nitrogen.
What are the uses of aniline in our daily lives?
Anilines have their uses in the rubber industry to process the rubber chemicals and products like car tyres, gloves, balloons, etc. It is also used as a dyeing agent for the manufacturing of clothes like jeans, etc. It is used for the production of drugs, for example, paracetamol, acetaminophen, and Tylenol.
Is aniline a carcinogen?
Human cancer data are insufficient to conclude that aniline is a cause of bladder tumors while animal studies indicate that aniline causes tumors of the spleen. EPA has classified aniline as a Group B2, probable human carcinogen.
What are the uses of aniline?
Aniline is used in rubber accelerators and anti-oxidants, dyes and intermediates, photographic chemicals, as isocyanates for urethane foams, in pharmaceuticals, explosives, petroleum refining; and in production of diphenylamine, phenolics, herbicides and fungicides.
What is the function of aniline?
Aniline, an organic base used to make dyes, drugs, explosives, plastics, and photographic and rubber chemicals.
How do you test for aniline?
Aromatic primary amines can be confirmed by azo dye test. Primary amine e.g. aniline reacts with nitrous acid generated in situ by the reaction of sodium nitrite with HCl at 0–5°C to produce diazonium salt. This couples with β-naphthol to give a scarlet red dye, which is sparingly soluble in water.
Why is aniline toxic?
Aniline can be toxic if ingested, inhaled, or by skin contact. Aniline damages hemoglobin, a protein that normally transports oxygen in the blood. The damaged hemoglobin can not carry oxygen. This condition is known as methemoglobinemia and its severity depends on how much you are exposed to and for how long.
What is aniline process?
Aniline (CAS No. 62-53-3) is produced by catalytic hydrogenation of nitrobenzene (CAS No. 98-95-3) in a continuous high efficiency liquid phase process. The process utilizes a proprietary catalyst made in the plant for maximum economy and selectivity. Aniline is a versatile chemical with increasing demand worldwide.
How to tell if aniline is a toxic substance?
1 difficulty breathing, shortness of breath, or chest pain 2 weakness, nausea, or vomiting 3 blood in the urine (brown- or bronze-colored urine) 4 blue, brown, or gray color of the skin, lips, or nailbeds
What kind of odor does aniline have?
Aniline has a characteristic aromatic or fishy odor which provides adequate warning of acute exposure. Aniline is rapidly absorbed after inhalation and ingestion. Aniline liquid and vapor are also absorbed well through skin, and this can contribute to systemic toxicity.
What kind of cancer is caused by aniline?
Chronic exposure may also result in effects on the blood. Human cancer data are insufficient to conclude that aniline is a cause of bladder tumors while animal studies indicate that aniline causes tumors of the spleen. EPA has classified aniline as a Group B2, probable human carcinogen.
What are the risks of exposure to aniline vapor?
Persons exposed only to aniline vapor do not pose risks of secondary contamination to others. Persons whose clothing or skin is contaminated with liquid aniline can cause secondary contamination by direct contact or through off-gassing vapor. Aniline vapor is heavier than air and may accumulate in low-lying areas. The vapor is combustible.