Which antimalarial drug can be given to a patient with G6PD deficiency? Primaquine is the only medicine approved for the radical cure of relapsing Plasmodium vivax malaria. However, the drug can lead to hemolytic anemia
Which antimalarial drug can be given to a patient with G6PD deficiency?
Primaquine is the only medicine approved for the radical cure of relapsing Plasmodium vivax malaria. However, the drug can lead to hemolytic anemia in recipients who are deficient in an enzyme, glucose 6-phosphate dehydrogenase (G6PD).
Can G6PD get malaria?
G6PD deficiency can potentially protect against uncomplicated malaria in African countries, but not severe malaria. Interestingly, this protection was mainly in heterozygous, being x-linked thus related to gender.
What drugs should G6PD avoid?
The following is a partial list of medications and chemicals that individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency should avoid:
- Acetanilid.
- Furazolidone.
- Isobutyl nitrite.
- Nalidixic acid.
- Naphthalene.
- Niridazole.
- Sulfa drugs.
What drugs can trigger G6PD?
Red blood cell destruction can be triggered by infections, certain foods (such as fava beans), and certain medicines, including:
- Antimalarial medicines such as quinine.
- Aspirin (high doses)
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Quinidine.
- Sulfa drugs.
- Antibiotics such as quinolones, nitrofurantoin.
Which antibiotics are safe in G6PD deficiency?
Antibiotics
- Sulphonamides (check with your doctor)
- Co-trimoxazole (Bactrim, Septrin)
- Dapsone.
- Chloramphenicol.
- Nitrofurantoin.
- Nalidixic acid.
What can you not eat if you have G6PD?
Table 1
| Foods/chemicals that should be avoided by G6PD‐deficient individuals | Foods/chemicals for which caution should be exercised during consumption |
|---|---|
| Fava beans Naphthalene Aniline dyes | Food colouring agent 1‐phenylazo‐2‐naphthol‐6‐sulphonic acid |
Can you donate blood if you have G6PD?
If you have G6PD (Glucose-6-Phosphate Dehydrogenase Deficiency) or Thalassemia (minor), you can donate blood if you meet the haemoglobin requirement.
What food should avoid if you have G6PD?
Your child should not eat fava beans. Some people should also avoid red wine, all beans, blueberries, soya products, tonic water and camphor.
What G6PD Cannot eat?
Medicines and foods to avoid with G6PD deficiency
- Foods to avoid: Fava beans.
- Medicines to avoid: Dapsone. Methylene blue. Nitrofurantoin. Pegloticase. Phenazopyridine. Primaquine. Rasburicase. Tafenoquine.
- Chemicals to avoid. Naphthalene (an ingredient found in moth balls)