What causes cutaneous larva migrans in humans?

What causes cutaneous larva migrans in humans?

Cutaneous larva migrans (CLM), also having been termed for the clinical sign of creeping eruption, is an infectious syndrome caused by multiple types of hookworms. This is most commonly transmitted by animal feces depositing eggs in the soil, with larvae entering humans through direct contact with skin.

How do you know if you have larva migrans?

Cutaneous larva migrans symptoms

1. Red, twisting lesions that grow. CLM presents as a red lesion that has a twisting, snake-like pattern.
2. Itchiness and discomfort. CLM lesions may itch, sting, or be painful.
3. Swelling. Swelling can also be present.
4. Lesions on the feet and backside.

What are larval migrans?

Larva migrans describes a parasitic disease involving migration of immature (larval) worms in various parts of the body. Several different worm species can be involved and migration occurs in one of three forms. When the worms migrate through the skin of the host, it is called cutaneous (skin) larva migrans.

How do humans get visceral larva migrans?

Humans (usually preschool children) acquire toxocariasis by ingesting soil contaminated by pup feces. Although most infections are subclinical, the infection can progress as the larvae invade the liver, lungs, CNS, and other sites.

What does hookworm skin infection look like?

Creeping eruption is a skin infection caused by hookworms. It can be caused by exposure to moist sand that has been contaminated by infected dog or cat stool. It appears as a winding, snakelike rash with blisters and itching.

What is the treatment for larva migrans?

Cutaneous larva migrans is self-limiting; migrating larvae usually die after 5–6 weeks. Albendazole is very effective for treatment. Ivermectin is effective but not approved for this indication. Symptomatic treatment for frequent severe itching may be helpful.