Where did varicella zoster virus originated?

Where did varicella zoster virus originated? Varicella zoster virus (VZV) is the causative agent of chickenpox and shingles. The geographic distribution of VZV clades was taken as evidence that VZV migrated out of Africa with

Where did varicella zoster virus originated?

Varicella zoster virus (VZV) is the causative agent of chickenpox and shingles. The geographic distribution of VZV clades was taken as evidence that VZV migrated out of Africa with human populations. We show that extant VZV strains most likely originated in Europe and not in Africa.

Is varicella zoster A virus?

Varicella (chickenpox) is an acute infectious disease. It is caused by varicella-zoster virus (VZV), which is a DNA virus that is a member of the herpesvirus group. After the primary infection, VZV stays in the body (in the sensory nerve ganglia) as a latent infection. Primary infection with VZV causes varicella.

What type of virus is varicella zoster?

Varicella-Zoster Virus (VZV) VZV is a DNA virus and is a member of the herpesvirus group. Like other herpesviruses, VZV persists in the body as a latent infection after the primary (first) infection; VZV persists in sensory nerve ganglia.

What cells does varicella zoster affect?

VZV is a highly species-specific virus which replicates efficiently in human cells such as fibroblasts and has been shown to infect T lymphocytes and neuronal cells (24, 38).

What is another name for varicella zoster virus?

Varicella-zoster virus (VZV) is the cause of chickenpox and herpes zoster (also called shingles). Chickenpox follows initial exposure to the virus and is typically a relatively mild, self-limited childhood illness with a characteristic exanthem.

How does varicella zoster virus affect the body?

Varicella is characterized by fever concurrent with a self-limiting rash on the skin and sometimes mucosa. Headache, malaise, and loss of appetite are also seen. The rash begins as macules, rapidly progresses to papules, followed by a vesicular stage and crusting of lesions. Crusts slough off after 1 to 2 weeks.

What is the normal range for varicella-zoster virus?

Reference Range(s)

Index Interpretation
<135.00 Negative – Antibody not detected
135.00-164.99 Equivocal
≥165.00 Positive – Antibody detected

What is another name for varicella-zoster virus?

How long does the varicella zoster virus live?

Chickenpox spreads very easily by touching chickenpox blisters or through the air when someone with chickenpox coughs or sneezes. The virus does not live long on surfaces. Once someone comes in contact with the virus, it usually takes about 2 weeks for chickenpox to appear, but it can range from 10 to 21 days.