What is radiosensitive tumor? Radiosensitive tumours are tumours which respond well to radiotherapy. Radiotherapy may be effective alone, or may require the addition of cytotoxic chemotherapy as in the more advanced stages of a Wilm’s
What is radiosensitive tumor?
Radiosensitive tumours are tumours which respond well to radiotherapy. Radiotherapy may be effective alone, or may require the addition of cytotoxic chemotherapy as in the more advanced stages of a Wilm’s tumour and Hodgkin’s disease. This group includes: malignant lymphomas.
What cancers are radiosensitive?
Two examples of highly radiosensitive cancers are leukemia (cancer of the blood cells) and lymphoma (cancer of the lymphatic system). Radiation therapy is most effective when a tumor is contained, easily accessible, and located away from major organs of the body.
Which drug is considered a radiosensitizer?
Hypoxic cell sensitizers are able to increase the radiosensitivity of tumor cells deficient of oxygen by inducing the formation and stabilization of DNA-toxic radicals, mimicking the effect of oxygen. These drugs include nitroimidazole, misonidazole, etanidazole, nimorazole, and efaproxaril.
Is SCC radiosensitive?
Purpose: Squamous cell carcinomas (SCCs) are characterized by moderate radiosensitivity. We have established the human head & neck SCC cell line SKX, which shows an exceptionally high radiosensitivity. It was the aim of this study to understand the underlying mechanisms.
What is the most radioresistant tumor?
The most radioresistant cell lines are fibrocytes, chondrocytes, myocytes and nerve cells. Consequently, the tumours which better tolerate radiation are fibrosarcoma, myosarcoma, glioma, osteosarcoma, etc. To sum up, radiotherapy has been used since more than a century to fight against some kinds of cancer.
Which is the most radiosensitive tumor?
Radiosensitive tumors include:
- Lymphoma.
- Myeloma.
- Seminoma.
Which organ is the most radiosensitive?
digestive tract
The digestive tract is among the most radiosensitive organs in the body and its function, which is partly regulated by gastrointestinal (GI) peptides, can be affected by radiation exposure.
What does radiation recall look like?
Radiation recall is a severe skin reaction that occurs when certain chemotherapy drugs are administered during or soon after radiation treatment. The rash appears like a severe sun burn. Treatment generally consists of corticosteroids to reduce inflammation, and rarely, delay of chemotherapy until the skin heals.
Which TM is least radiosensitive?
1. Histologic type • High sensitivity: Malignant lymphoma, Seminoma, etc. Moderate sensitivity: Epithelial tumor (Carcinoma) • Low sensitivity: Osteosarcoma, Malignant melanoma, etc. 2.
Which tumor is most sensitive to radiotherapy?
Embryonal tumors, as well as tumors composed of rapidly growing cells, are sensitive to radiotherapy. Lymphoid cells are particularly susceptible to radiation. On the contrary, neurosarcoma, glioma and melanoma are radioresistant.
What cell is most sensitive to radiation?
Amongst the body cells, the most sensitive are spermatogonia and erythroblasts, epidermal stem cells, gastrointestinal stem cells. The least sensitive are nerve cells and muscle fibers. Very sensitive cells are also oocytes and lymphocytes, although they are resting cells and do not meet the criteria described above.
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