What is Hypotransferrinemia?

What is Hypotransferrinemia? Related Disorders Acquired hypotransferrinemia is a condition characterized by low levels of the protein transferrin in the body, which results in the accumulation of iron in various organs of the body. Unlike,

Related Disorders Acquired hypotransferrinemia is a condition characterized by low levels of the protein transferrin in the body, which results in the accumulation of iron in various organs of the body. Unlike, congenital or hereditary atransferrinemia, this condition is acquired and not genetic.

What is ferritin responsible for?

Ferritin, an iron storage protein, is the primary iron storage mechanism and is critical to iron homeostasis. Ferritin makes iron available for critical cellular processes while protecting lipids, DNA, and proteins from the potentially toxic effects of iron.

What does a high transferrin level mean?

understanding the transferrin test results High transferrin means the liver is producing more of the protein to use all the iron available in the body. Low transferrin level means the body is absorbing more iron then needed.

What does ferritin mean in a blood test?

Ferritin is a protein that contains iron and is the primary form of iron stored inside of cells. The small amount of ferritin that is released and circulates in the blood is a reflection of the total amount of iron stored in the body. This test measures the amount of ferritin in the blood.

What is high iron called?

Hemochromatosis, or iron overload, is a condition in which your body stores too much iron. It’s often genetic. It can cause serious damage to your body, including to your heart, liver and pancreas. You can’t prevent the disease, but early diagnosis and treatment can avoid, slow or reverse organ damage.

How does haemochromatosis affect the body?

Hereditary hemochromatosis (he-moe-kroe-muh-TOE-sis) causes your body to absorb too much iron from the food you eat. Excess iron is stored in your organs, especially your liver, heart and pancreas. Too much iron can lead to life-threatening conditions, such as liver disease, heart problems and diabetes.

What is ferritin a marker of?

Ferritin is used a marker of iron deficiency in various healthcare facilities across the globe [14]. Being an acute phase reactant, serum ferritin level is prone to be higher in overweight and obese people, because of a state of subclinical, but generalized inflammation in them [15–17].

Can stress increase ferritin levels?

In contrast, chronic inflammation and oxidative stress may act as a link between elevated serum-ferritin levels, which may contribute to cellular or tissue damage [10].

What are the symptoms of too much iron?

Early symptoms of iron poisoning may include stomach pain, nausea and vomiting. Gradually, the excess iron accumulates in internal organs, causing potentially fatal damage to the brain and liver.

What happens if ferritin is high?

If a ferritin test shows higher than normal levels, it could indicate that you have a condition that causes your body to store too much iron. It could also point to liver disease, rheumatoid arthritis, other inflammatory conditions or hyperthyroidism.

What diseases cause low ferritin?

Summary of Diseases Associated With Lower Ferritin