Can Lupoid Onychodystrophy be cured?

Can Lupoid Onychodystrophy be cured? It is an immune-mediated condition that affects your dog’s nails and paws. It is considered a type of lupus your dog can suffer from and therefore cannot be passed on

Can Lupoid Onychodystrophy be cured?

It is an immune-mediated condition that affects your dog’s nails and paws. It is considered a type of lupus your dog can suffer from and therefore cannot be passed on to other animals or to humans. While there is no cure, there is treatment and management.

What causes SLO?

SLOS is caused by a deficiency of the enzyme 7-dehydrocholesterol reductase. The enzyme deficiency occurs as the result of an abnormal DHCR7 gene inherited from each parent. SLOS is an autosomal recessive genetic disorder.

What is Lupoid Onychodystrophy?

Lupoid onychodystrophy, sometimes called lupoid onychitis, is a disease that affects the toenails or claws of dogs. The disease usually affects multiple claws on all four paws.

How is slo treated?

Mueller et al (3) considered tetracycline or doxycycline and niacinamide useful combinations for the treatment of SLO. The combination of tetracycline and niacinamide plus fatty acid supplementation and a high fatty acid diet is the initial treatment of choice at our facility.

What does Onychodystrophy mean?

Onychodystrophy is a widely used, yet rarely defined term. It refers to nail changes apart from changes of the color called nail dyschromia. From the patient’s point of view partial or complete disruption of the various keratinous layers of the nail plate is most relevant.

What is Onychodystrophy?

Is Slo an autoimmune disease?

These alleles are associated with risk for the development of SLO in the Gordon setter, supporting the theory that SLO is indeed an autoimmune disease (2). There may be an association between thyroid disease and SLO.

Is onychodystrophy curable?

Thus, at least in part onychodystrophy is curable if antagonizing the pathogenetically relevant reason. However, about 20-30% of the patients must expect treatment failure or relapse following treatment of onychomycosis [36].