What are the side effects of trabectedin?

What are the side effects of trabectedin?

What are the most common side effects of YONDELIS®?

• Nausea.
• Tiredness.
• Vomiting.
• Constipation.
• Decreased appetite.
• Diarrhea.
• Swelling of your hands, ankles, or feet.
• Shortness of breath.

What does trabectedin do to cells?

Trabectedin works by sticking to the DNA in cells and damaging it. This stops the cancer cells growing and multiplying.

What type of chemo is trabectedin?

Drug Type: Trabectedin is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.

What is Yondelis used for?

YONDELIS® is a prescription medicine used to treat people with liposarcoma or leiomyosarcoma that cannot be treated with surgery or has spread to other areas of the body, and who have received treatment with certain other medicines. It is not known if YONDELIS® is safe and effective in children.

Does trabectedin cause hair loss?

LESS COMMON SIDE EFFECTS OF TRABECTEDIN Hair loss normally starts after your first or second cycle of chemotherapy. It is almost always temporary, and the hair will continue to grow after you finish your treatment. Your nurse can give you advice on how to cope with losing your hair.

How effective is Yondelis?

Patients who received trabectedin in Study 1 showed a significant improvement in progression-free survival —a 45% reduction in the risk for disease progression or death compared with patients who received dacarbazine (Table).

How much does trabectedin cost?

About 2,000 people a year develop the cancer in the UK, of whom 500 to 600 have an advanced form. Trabectedin costs £3,500 to £5,000 per infusion, which is given every three weeks to one month.

Is Zepzelca a chemo drug?

ZEPZELCA is indicated for the treatment of adult patients with metastatic small cell lung cancer (SCLC) with disease progression on or after platinum-based chemotherapy. This indication is approved under accelerated approval based on overall response rate and duration of response [see Clinical Studies].

Is trabectedin approved by FDA?

On October 23, the Food and Drug Administration (FDA) approved trabectedin (Yondelis®) for the treatment of two subtypes of soft tissue sarcomas: liposarcoma and leiomyosarcoma.

Who makes Yondelis?

D., Clinical Leader, YONDELIS, Janssen Research & Development, LLC. “We are proud that our Phase 3 study is the largest ever conducted in this patient population and we’re delighted that patients in the U.S. can now benefit from the treatment.”

Is Zepzelca chemo or immunotherapy?

What are the side effects of Zepzelca?

Side Effects Tiredness, joint/muscle ache/pain, constipation or diarrhea, abdominal pain, nausea, vomiting, or loss of appetite may occur. Nausea and vomiting can be severe. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting.